Google DeepMind Releases Gene Prediction Model AlphaGenome 2

Google DeepMind has released the gene prediction model AlphaGenome 2. This model can predict the function of DNA under specified conditions, based on approximately one million base pairs of DNA sequences and designated tissues, cell types, or states. It covers gene expression, histone modifications, chromatin accessibility, and introduces DNA methylation. The new model predicts for a single condition at a time, can distinguish closely related cell types, and generalizes to new single-cell data without the need for retraining. DeepMind claims that it has identified nearly twice the number of variants affecting cell gene expression compared to previous state-of-the-art models. AlphaGenome 2 is now accessible to non-commercial research via the AlphaGenome API, while commercial research is in private testing, with related Skills set to launch soon on Google's agent development platform Antigravity.

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